Ma, Juan’s team published research in Synthesis in 2019-02-28 | CAS: 123-39-7

Synthesis published new progress about Acylation. 123-39-7 belongs to class amides-buliding-blocks, name is N-Methylformamide, and the molecular formula is C2H5NO, Application In Synthesis of 123-39-7.

Ma, Juan published the artcileMn(II)-Catalyzed N-Acylation of Amines, Application In Synthesis of 123-39-7, the main research area is substituted amide preparation; amide amine acylation manganese catalyst; amine amide formylation manganese catalyst.

A protocol for synthesis of N-substituted amides such as R1R2NC(O)R3 [R1 = C6H5, C6H5CH2, 4-MeOC6H4CH2, etc.; R2 = H, Me, Et; R3 = H, Me, Et] was developed via Mn-catalyzed N-acylation/formylation of amines with high yields using N,N-dimethylformamide and other amides as the carbonyl source. The protocol was simple, does not require any acid, base, ligand or other additives and encompassed a broad substrate scope such as primary, secondary and heterocyclic amines.

Synthesis published new progress about Acylation. 123-39-7 belongs to class amides-buliding-blocks, name is N-Methylformamide, and the molecular formula is C2H5NO, Application In Synthesis of 123-39-7.

Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics