Boettcher, Stephan published the artcileIndoxylic Acid Esters as Convenient Intermediates Towards Indoxyl Glycosides, Application In Synthesis of 125328-80-5, the main research area is dye pigment indoxyl glycoside preparation glycosylation decarboxylation silver catalyst.
Indoxylic acid Me and allyl esters with varied halide-substitution patterns were obtained in excellent yields using a scalable route. Phase-transfer glycosylation of these key intermediates was carried out with various glycosyl halides. Subsequent mild silver-mediated decarboxylation followed by Zemplen deacetylation led to indoxyl glycosides, e.g. I, in good overall yields. Indoxyl glycosides are well-established and widely used tools for enzyme screening and enzyme-activity monitoring. In the past, their synthesis has been difficult, so this new approach has led to a variety of useful structures.
European Journal of Organic Chemistry published new progress about Deacetylation. 125328-80-5 belongs to class amides-buliding-blocks, name is N-(4-Bromo-3-chloro-2-methylphenyl)acetamide, and the molecular formula is C9H9BrClNO, Application In Synthesis of 125328-80-5.
Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics