Bhise, Nandu Baban published the artcileSynthesis of potential impurities of bicalutamide, Recommanded Product: N-(4-Cyano-3-(trifluoromethyl)phenyl)-3-((2-fluorophenyl)sulfonyl)-2-hydroxy-2-methylpropanamide, the main research area is bicalutamide impurity synthesis.
During the bulk synthesis of bicalutamide (bical), which is an oral nonsteroidal, anti-androgen drug used for prostate cancer, various impurities are formed. The present work details the development of simple processes for the preparation of impurities of bicalutamide, viz bical-sulfoxides, bical-deshydroxy, bical-desfluoro, bical-2-fluoro, and bical-3-fluoro derivatives
Synthetic Communications published new progress about bicalutamide impurity synthesis. 1159977-36-2 belongs to class amides-buliding-blocks, name is N-(4-Cyano-3-(trifluoromethyl)phenyl)-3-((2-fluorophenyl)sulfonyl)-2-hydroxy-2-methylpropanamide, and the molecular formula is C18H14F4N2O4S, Recommanded Product: N-(4-Cyano-3-(trifluoromethyl)phenyl)-3-((2-fluorophenyl)sulfonyl)-2-hydroxy-2-methylpropanamide.
Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics