Owen, Aniekan Ekpenyong published the artcileManganese-Catalyzed Dehydrogenative Synthesis of Urea Derivatives and Polyureas, Related Products of amides-buliding-blocks, the main research area is amine methanol manganese catalyst dehydrogenative coupling reaction; formamide amine manganese catalyst dehydrogenative coupling reaction; urea preparation.
Here the synthesis of (poly)ureas using much less toxic reagents-(di)amines and methanol-via a catalytic dehydrogenative coupling process. The reaction was catalyzed by a pincer complex of an earth-abundant metal, manganese, and liberates H2 gas, valuable by itself, as the only byproduct, making the overall process highly atom-economic. A broad variety of sym. and unsym. urea derivatives and polyureas was synthesized in moderate to quant. yields using this catalytic protocol. Mechanistic insights was also been provided using experiments and DFT computation, suggesting that the reaction proceeds via an isocyanate intermediate.
ACS Catalysis published new progress about Activation energy. 123-39-7 belongs to class amides-buliding-blocks, name is N-Methylformamide, and the molecular formula is C2H5NO, Related Products of amides-buliding-blocks.
Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics