Mohammad, Haroon published the artcileDiscovery and characterization of potent thiazoles versus methicillin- and vancomycin-resistant Staphylococcus aureus, COA of Formula: C11H15NS, the main research area is thiazole antibacterial Staphylococcus antibiotic resistance.
Methicillin- and vancomycin-resistant Staphylococcus aureus (MRSA and VRSA) infections are growing global health concerns. Structure-activity relationships of phenylthiazoles as a new antimicrobial class have been addressed. The authors present 10 thiazole derivatives that exhibit strong activity against 18 clin. strains of MRSA and VRSA with acceptable PK profile. Three derivatives revealed an advantage over vancomycin by rapidly eliminating MRSA growth within 6 h, and no derivatives are toxic to HeLa cells at 11 μg/mL.
Journal of Medicinal Chemistry published new progress about Antibacterial agents. 1208077-46-6 belongs to class amides-buliding-blocks, name is 4-Butylthiobenzamide, and the molecular formula is C11H15NS, COA of Formula: C11H15NS.
Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics