Kadam, Abhishek A. published the artcileNi-Catalyzed Three-Component Alkene Carboacylation Initiated by Amide C-N Bond Activation, Computed Properties of 7465-88-5, the main research area is alkene amide tetraarylborate nickel catalyst chemoselective diastereoselective carboacylation; functionalized ketone stereoselective preparation.
The nickel-catalyzed intermol. carboacylation of alkenes with amides and tetraarylborates is presented. Bicyclic alkenes are readily functionalized with a variety of N-benzoyl-N-phenylbenzamides and triarylboranes, which are generated in situ from the corresponding tetraarylborates, to synthesize ketone products in up to 91% yield. Preliminary mechanistic studies suggest that migratory insertion precedes transmetalation and that reductive elimination is the turnover-limiting step. These reactions occur with excellent chemoselectivity and diastereoselectivity in the absence of a directing/chelating group and further demonstrate amides as practical acyl electrophiles for alkene dicarbofunctionalization reactions.
ACS Catalysis published new progress about Acylation catalysts. 7465-88-5 belongs to class amides-buliding-blocks, name is 4-Methoxy-N-phenylbenzamide, and the molecular formula is C14H13NO2, Computed Properties of 7465-88-5.
Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics