Yin, Jiawen’s team published research in Organic Letters in 2019-01-18 | CAS: 123-39-7

Organic Letters published new progress about Acylation (of aromatic amines). 123-39-7 belongs to class amides-buliding-blocks, name is N-Methylformamide, and the molecular formula is C2H5NO, Related Products of amides-buliding-blocks.

Yin, Jiawen published the artcileCatalyst-Free Transamidation of Aromatic Amines with Formamide Derivatives and Tertiary Amides with Aliphatic Amines, Related Products of amides-buliding-blocks, the main research area is transamidation aromatic amine formamide derivative tertiary amide aliphatic amine.

A simple catalyst- and promoter-free protocol has been developed for the transamidation of weakly nucleophilic aromatic amines with formamide derivatives and low-reactivity tertiary amides with aliphatic amines. This strategy is advantageous because no catalyst or promoters are needed, no additives are required, separation and purification is easy, and the reaction is scalable. Significantly, this strategy was further applied to synthesize several pharmaceutical mols. on a gram scale, and excellent yields were achieved.

Organic Letters published new progress about Acylation (of aromatic amines). 123-39-7 belongs to class amides-buliding-blocks, name is N-Methylformamide, and the molecular formula is C2H5NO, Related Products of amides-buliding-blocks.

Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics