Wang, Kaixuan published the artcileCatalytic asymmetric [3+2] cycloaddition of isomunchnones with methyleneindolinones, Application of N-Methylformamide, the main research area is chiral oxa bridged spiropiperidine oxindole preparation enantio diastereoselective; diazoimide methyleneindolinone dipolar cycloaddition rhodium zinc catalyst.
An efficient enantioselective [3+2] cycloaddition of isomunchnones with methyleneindolinones that are generated by an in situ intramol. addition of the carbonyl group to rhodium carbenes is realized with a chiral N,N’-dioxide/Zn(II) complex as a Lewis acid. A series of chiral oxa-bridged 3-spiropiperidines are obtained in high yields with excellent dr and excellent ee values.
Chemical Communications (Cambridge, United Kingdom) published new progress about 1,3-Dipolar cycloaddition catalysts. 123-39-7 belongs to class amides-buliding-blocks, name is N-Methylformamide, and the molecular formula is C2H5NO, Application of N-Methylformamide.
Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics