Wang, Shi-Meng published the artcileClickable coupling of carboxylic acids and amines at room temperature mediated by SO2F2: A significant breakthrough for the construction of amides and peptide linkages, Product Details of C14H13NO2, the main research area is peptide linkage click coupling carboxylic acid amine; amide preparation click coupling carboxylic acid amine sulfonyl fluoride; amine carboxylic acid click coupling sulfonyl fluoride.
A mild, simple, efficient and robust protocol was developed for the synthesis of amides RC(O)NR1R2 [R = Et, Ph, 2-furyl, 4-pyridyl, etc., R1 = H, Et, Bn, etc., R2 = Et, Ph, 3-pyridyl, etc.] via SO2F2-mediated clickable coupling of carboxylic acids with amines. Peptide linkages were also prepared using this methodol. The direct click reactions of acids and amines on gram scale were also demonstrated using an extremely easy work-up and purification process of washing with 1 M aqueous HCl to provide the desired amides in greater than 99% purity and excellent yields.
Organic & Biomolecular Chemistry published new progress about Amides Role: SPN (Synthetic Preparation), PREP (Preparation). 7465-88-5 belongs to class amides-buliding-blocks, name is 4-Methoxy-N-phenylbenzamide, and the molecular formula is C14H13NO2, Product Details of C14H13NO2.
Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics