Sun, Shaofa published the artcileFrom imines to amides via NHC-mediated oxidation, Synthetic Route of 7465-88-5, the main research area is amide preparation green chem; imine oxidation heterocyclic carbene.
The unprecedented NHC-mediated oxidation of imines RCH=NR1 (R = Ph, 1-naphthyl, 4-pyridyl, etc.; R1 = Ph, Tosyl, Boc, etc.) to amides RC(O)NHR1 is described. This protocol features broad substrate scope and allows rapid assembly of amides in good to high yields. Notably, this process includes not only the umpolung of imines, but also the discovery of NHC-bound 1,2-dioxetane intermediates.
Organic Chemistry Frontiers published new progress about Amides Role: SPN (Synthetic Preparation), PREP (Preparation). 7465-88-5 belongs to class amides-buliding-blocks, name is 4-Methoxy-N-phenylbenzamide, and the molecular formula is C14H13NO2, Synthetic Route of 7465-88-5.
Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics