Kumar, Vishal published the artcileCu-catalysed transamidation of unactivated aliphatic amides, Computed Properties of 123-39-7, the main research area is amino phenyl alkylamide copper catalyst tranamidation; phenyl amide preparation.
Direct transamidation was gaining prominence as a ground-breaking technique that generates a wide variety of amides without the requirement of acid-amine coupling or other intermediate steps. However, transamidation of unactivated aliphatic amides, on the other hand, was a long-standing issue in comparison to transamidation of activated amides. Herein, a transamidation approach of an unactivated aliphatic amide using a copper catalyst and chlorotrimethylsilane as an additive was reprted. In addition, used transamidation as a tool for selective N-C(O) cleavage and O-C(O) formation to synthesize 2-substituted benzoxazoles and benzothiazoles. The reactions were carried out without using any solvents and offered wide substitution scope.
Organic & Biomolecular Chemistry published new progress about Amides Role: SPN (Synthetic Preparation), PREP (Preparation). 123-39-7 belongs to class amides-buliding-blocks, name is N-Methylformamide, and the molecular formula is C2H5NO, Computed Properties of 123-39-7.
Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics