Khaliullin, F. A. published the artcileUnusual Reaction of 8-Bromo-3-methyl-7-(thietan-3-yl)3,7-dihydro-1H-purine-2,6-diones with Trisamine in Dimethylformamide, Related Products of amides-buliding-blocks, the main research area is dimethylamino methylthietanyl dihydropurine dione preparation; bromo methylthietanyl dihydropurine dione DMF nucleophilic substitution reaction.
The reaction of title compounds I (R = H, Et, pentyl, benzyl, etc.; R1 = Br) with trisamine in DMF gave, instead of the expected 8-tris(hydroxymethyl)methylamino-substituted products I (R1 = NHC(CH2OH)3), 8-dimethylamino-substituted products I (R1 = N(CH3)2). The formation of unusual reaction products was explained by the initial reaction of DMF with trisamine to form dimethylamine and subsequent nucleophilic substitution reaction of the latter with the bromine atom.
Russian Journal of Organic Chemistry published new progress about Formamides Role: RCT (Reactant), RACT (Reactant or Reagent). 123-39-7 belongs to class amides-buliding-blocks, name is N-Methylformamide, and the molecular formula is C2H5NO, Related Products of amides-buliding-blocks.
Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics