Devi, E. Sankari published the artcileN-Heterocyclic Carbene Catalyzed Synthesis of Trisubstituted Epoxides via Tandem Amidation/Epoxidation Sequence, Name: N-Methylformamide, the main research area is chalcone preparation formamide TBHP NHC catalyst tandem amidation epoxidation; benzoyl aryloxiranyl carboxamide diastereoselective preparation green chem.
A tandem amidation/epoxidation sequence between various substituted chalcones and N,N-dimethylformamide (DMF) for the synthesis of trisubstituted epoxides employing N-heterocyclic carbene catalysis was developed. This reaction was performed under metal-free conditions in the presence of tert-Bu hydroperoxide (TBHP) as the oxidant. Trisubstituted epoxides bearing a ketone and an amide functionality (N,N-di-Me formyl group) were synthesized starting from a wide range of chalcones in moderate to good yields with excellent diastereoselectivity.
Organic Letters published new progress about Acetophenones Role: RCT (Reactant), RACT (Reactant or Reagent). 123-39-7 belongs to class amides-buliding-blocks, name is N-Methylformamide, and the molecular formula is C2H5NO, Name: N-Methylformamide.
Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics