Chen, Hao published the artcileEnantioselective Twofold C-H Annulation of Formamides and Alkynes without Built-in Chelating Groups, Recommanded Product: N-Methylformamide, the main research area is ferrocene based formamide preparation nickel catalyzed oxidative annulation alkyne; chiral benzyldiphenyl ferrocenopyridinone preparation crystal structure; mol structure chiral benzyldiphenyl ferrocenopyridinone; aluminum; annulation; ferrocenes; formamides; nickel.
Twofold C-H annulation of readily available formamides and alkynes without built-in chelating groups was achieved. Ni-Al bimetallic catalysis enabled by a bulky BINOL-derived chiral secondary phosphine oxide (SPO) ligand proved to be critical for high reactivity and high selectivity. This reaction uses readily available formamides as starting materials and provides a concise synthetic pathway to a broad range of chiral ferrocenes in 40-98% yield and 93-99% ee.
Angewandte Chemie, International Edition published new progress about Alkynes Role: RCT (Reactant), RACT (Reactant or Reagent). 123-39-7 belongs to class amides-buliding-blocks, name is N-Methylformamide, and the molecular formula is C2H5NO, Recommanded Product: N-Methylformamide.
Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics