Dawood, Rafid S. published the artcileStereodivergent Total Syntheses of (+)-Monomorine I and (+)-Indolizidine 195B, Formula: C4H11NOS, the main research area is indolizidine alkaloid preparation diastereoselective enantioselective; monomorine alkaloid preparation diastereoselective enantioselective.
A simple and efficient stereoselective total synthesis of two natural products (+)-monomorine I and (+)-indolizidine 195B in high yields starting from a readily available alc. is described. The key step in this synthetic route exploits the judicious use of solvent to enable a closed or open transition state in a nucleophilic addition of Grignard reagent to sulfinimine, giving selective access to two distinct diastereomers required for the formation of the two target natural products.
European Journal of Organic Chemistry published new progress about Alkaloids Role: SPN (Synthetic Preparation), PREP (Preparation). 343338-28-3 belongs to class amides-buliding-blocks, name is (S)-2-Methylpropane-2-sulfinamide, and the molecular formula is C4H11NOS, Formula: C4H11NOS.
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