On May 31, 2022, Chibwe, Leah; Parrott, Joanne L.; Shires, Kallie; Khan, Hufsa; Clarence, Stacey; Lavalle, Christine; Sullivan, Cheryl; O鈥睟rien, Anna M.; De Silva, Amila O.; Muir, Derek C. G.; Rochman, Chelsea M. published an article.Synthetic Route of 102-07-8 The title of the article was A Deep Dive into the Complex Chemical Mixture and Toxicity of Tire Wear Particle Leachate in Fathead Minnow. And the article contained the following:
The ecol. impact of tire wear particles in aquatic ecosystems is a growing environmental concern. We combined toxicity testing, using fathead minnow (Pimephales promelas) embryos, with nontarget high-resolution liquid chromatog. Orbitrap mass spectrometry to characterize the toxicity and chem. mixture of organic chems. associated with tire particle leachates. We assessed: 1) exposure to tire particle leachates after leaching for 1-, 3-, and 10-d; and 2) the effect of the presence and absence of small tire particulates in the leachates. We observed a decrease in embryonic heart rates, hatching success, and lengths, as well as an increase in the number of embryos with severe deformities and diminished eye and body pigmentation, after exposure to the leachates. Overall, there was a pattern whereby we observed more toxicity in the 10-d leachates, and greater toxicity in unfiltered leachates. Redundancy anal. showed that several benzothiazoles and aryl-amines were correlated with the toxic effects observed in the embryos. These included benzothiazole, 2-aminobenzothiazole, 2-mercaptobenzothiazole, N,N鈥?diphenylguanidine, and N,N鈥?diphenylurea. However, many other chems. characterized as unknowns are likely to also play a key role in the adverse effects observed Our study provides insight into the types of chems. likely to be important toxicol. drivers in tire leachates, and improves our understanding of the ecotoxicol. impacts of tire wear particles. Environ Toxicol Chem 2021;00:1-10. 2021 The Authors. Environmental Toxicol. and Chem. published by Wiley Periodicals LLC on behalf of SETAC. The experimental process involved the reaction of 1,3-Diphenylurea(cas: 102-07-8).Synthetic Route of 102-07-8
The Article related to pimephales chem mixture tire wear particle toxicol, complex chemical mixtures, fathead minnow, tire toxicity, tire wear particles, Placeholder for records without volume info and other aspects.Synthetic Route of 102-07-8
Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics