On December 31, 2008, Singh, P. P.; Singh, R. B.; Kiran, S.; Tiwari, Anand; Rao, V. Goverdhan published an article.SDS of cas: 97-09-6 The title of the article was QSAR study of sulfonamides as inhibitors of carbonic anhydrase. And the article contained the following:
Quantum chem. reactivity descriptors based QSAR study of 48 sulfonamide derivatives as inhibitors of carbonic anhydrase has been studied in three different sets. The best QSAR model has correlation coefficient above 0.84 in one set the other two sets have the corresponding values above 0.79 and 0.81. The most important descriptor is heat of formation followed by mol. weight and total energy. The combination of descriptors providing the best model are heat of formation, mol. weight, total energy and LUMO energy. The CA enzyme-sulfonamide reaction appears to be favored by energy change. The experimental process involved the reaction of 3-Nitro-4-chlorobenzenesulfonamide(cas: 97-09-6).SDS of cas: 97-09-6
The Article related to quant structure activity relationship sulfonamide carbonic anhydrase inhibitor, Pharmacology: Structure-Activity and other aspects.SDS of cas: 97-09-6
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Amide – an overview | ScienceDirect Topics