Phadni, A.; Sharma, A. S.; Sharma, V.; Khadikar, P. V. published an article in 2012, the title of the article was QSAR study on carbonic anhydrase inhibition activity and related parameters using -SO2NH2 NMR chemical shift and topological indices.Recommanded Product: 3-Nitro-4-chlorobenzenesulfonamide And the article contains the following content:
The QSAR calculations of biol. activities like carbonic anhydrase inhibition, diuretic activity and lgP have been attempted on some sulfonamides using NMR chem. shift of the -SO2NH2 protons and a large set of topol. indexes: the Randic connectivity and the Balaban indexes. Regression anal. shows excellent results in multiparametric modeling. Results indicate that NMR chem. shift can be successfully used for modeling carbonic anhydrase inhibition constant (pki) and diuretic activity (pC), but plays no part in modeling lipophilicity (lg P) of sulfonamides. The experimental process involved the reaction of 3-Nitro-4-chlorobenzenesulfonamide(cas: 97-09-6).Recommanded Product: 3-Nitro-4-chlorobenzenesulfonamide
The Article related to carbonic anhydrase inhibitor qsar sulfonamide lipophilicity diuretic nmr, Pharmacology: Structure-Activity and other aspects.Recommanded Product: 3-Nitro-4-chlorobenzenesulfonamide
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