Yang, Peng; Wang, Xiuhua; Ma, Yu; Sun, Yaxin; Zhang, Li; Yue, Jieyu; Fu, Kaiyue; Zhou, Jianrong Steve; Tang, Bo published an article in 2020, the title of the article was Nickel-catalyzed C-alkylation of thioamides, amides and esters by primary alcohols through a hydrogen autotransfer strategy.Product Details of 685-91-6 And the article contains the following content:
A simple catalyst of Ni(OAc)2 and P(t-Bu)3 enables selective C-alkylation of thioacetamides and primary acetamides with alcs. for the first time. Monoalkylation of thioamides, amides and t-Bu esters occurs in excellent yields (>95%). Mechanistic studies reveal that the reaction proceeds via a hydrogen autotransfer pathway. The experimental process involved the reaction of N,N-Diethylacetamide(cas: 685-91-6).Product Details of 685-91-6
The Article related to thioamide amide ester alkylation primary alc nickel catalyst chemoselective, General Organic Chemistry: Synthetic Methods and other aspects.Product Details of 685-91-6
Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics