On August 16, 2019, Xu, Jian-Xing; Wu, Xiao-Feng published an article.Synthetic Route of 5455-98-1 The title of the article was Cobalt-Catalyzed Alkoxycarbonylation of Epoxides to 尾-Hydroxyesters. And the article contained the following:
Herein, the authors developed a new and practical catalytic system for the carbonylative synthesis of 尾-hydroxyesters. By using simple, cheap, and air-stable cobalt(II) bromide as the catalyst, combined with pyrazole and catalytic amount of manganese, active cobalt complex can be generated in situ and can catalyze various epoxides to give the corresponding 尾-hydroxyesters in moderate to excellent yields. Mechanism studies indicate that pyrazole plays a crucial role in this reaction. Moreover, with the addition of the catalytic amount of manganese, the active cobalt catalyst can be regenerated, which provides a possibility for reusing the cobalt catalyst. The experimental process involved the reaction of 2-(Oxiran-2-ylmethyl)isoindoline-1,3-dione(cas: 5455-98-1).Synthetic Route of 5455-98-1
The Article related to hydroxyester beta preparation cobalt catalyst epoxide alkoxycarbonylation, General Organic Chemistry: Synthetic Methods and other aspects.Synthetic Route of 5455-98-1
Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics