Li, Wenjing; Yin, Changzhen; Yang, Xiao; Liu, Hailong; Zheng, Xueli; Yuan, Maolin; Li, Ruixiang; Fu, Haiyan; Chen, Hua published an article in 2017, the title of the article was Cu(II)-Mediated keto C(sp3)-H bond 伪-acyloxylation of N,N-dialkylamides with aromatic carboxylic acids.Safety of N,N-Diethylacetamide And the article contains the following content:
The selective oxidative coupling of aromatic carboxylic acids with the C(sp3)-H bond adjacent to the keto group of alkylamides was developed by employing a low cost copper source. This provides an efficient approach for synthesis of O-benzoylglycolamides. The protocol displayed good functional group tolerance. A broad range of benzoic acids directly coupled with alkylamides to afford a variety of O-benzoylglycolamides in moderate to good yields. In addition, a reasonable radical mechanism was proposed based on EPR experiments The experimental process involved the reaction of N,N-Diethylacetamide(cas: 685-91-6).Safety of N,N-Diethylacetamide
The Article related to copper catalyst acyloxylation dialkylamide aromatic carboxylic acid, benzoylglycolamide preparation, General Organic Chemistry: Synthetic Methods and other aspects.Safety of N,N-Diethylacetamide
Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics