Kumar, Vishal; Dhawan, Sanjeev; Bala, Renu; Mohite, Sachin Balaso; Singh, Parvesh; Karpoormath, Rajshekhar published an article in 2022, the title of the article was Cu-catalysed transamidation of unactivated aliphatic amides.Quality Control of N,N-Diethylacetamide And the article contains the following content:
Direct transamidation was gaining prominence as a ground-breaking technique that generates a wide variety of amides without the requirement of acid-amine coupling or other intermediate steps. However, transamidation of unactivated aliphatic amides, on the other hand, was a long-standing issue in comparison to transamidation of activated amides. Herein, a transamidation approach of an unactivated aliphatic amide using a copper catalyst and chlorotrimethylsilane as an additive was reprted. In addition, used transamidation as a tool for selective N-C(O) cleavage and O-C(O) formation to synthesize 2-substituted benzoxazoles and benzothiazoles. The reactions were carried out without using any solvents and offered wide substitution scope. The experimental process involved the reaction of N,N-Diethylacetamide(cas: 685-91-6).Quality Control of N,N-Diethylacetamide
The Article related to amino phenyl alkylamide copper catalyst tranamidation, phenyl amide preparation, General Organic Chemistry: Synthetic Methods and other aspects.Quality Control of N,N-Diethylacetamide
Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics