On June 25, 2019, Zhou, Qilin; Zhang, Fenghua; Xie, Jianhua; Wang, Lixin published a patent.Related Products of 65645-88-7 The title of the patent was Chiral spiro phosphine-amino-oxazoline tridentate ligand, its preparation method and application. And the patent contained the following:
A chiral spiro phosphine-amino-oxazoline tridentate ligand having ruthenium complex exhibits high catalytic activity (TON to 10,000) and enantioselectivity (up to 98% ee) in the asym. hydrogenation of α-ketoamide, which has practical value is provided. The chiral spiro phosphine-amino-oxazoline tridentate ligand comprises a compound of formula I or an enantiomer, racemate, or a catalytically acceptable salt thereof, and having a main structural feature of having a chiral spiroindoline skeleton and having a chiral oxazoline group. The method for preparing a chiral spiro phosphine-amino-oxazoline tridentate ligand by racemic or optically active 7-diaryl/alkylphosphino-7/-aminospiroindole represented by formula 1 having a chiral spiroindoline skeleton used as a starting material. The chiral spiro phosphine-amino-oxazoline tridentate ligand forms a complex with the transition metal salt and can be used to catalyze the asym. catalytic hydrogenation of the carbonyl compound The experimental process involved the reaction of (S)-2-Hydroxy-N-methyl-2-phenylacetamide(cas: 65645-88-7).Related Products of 65645-88-7
The Article related to chiral spiro phosphine amino oxazoline preparation enantioselective hydrogenation catalyst, Organometallic and Organometalloidal Compounds: Phosphorus Compounds and other aspects.Related Products of 65645-88-7
Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics