On July 31, 2018, Zhang, Yinsheng; Gao, Yong; Ren, Jing; Wang, Qinglin; Zhao, Damin; Zhou, Yu; Wu, Zheyang published a patent.Synthetic Route of 16230-24-3 The title of the patent was Preparation of boron-containing compounds as tyrosine kinase inhibitors. And the patent contained the following:
The title compounds I [wherein R1 is H, F, Cl, Br, alkyl, etc.; X is NH or O; R4 and R6 are independently H, alkyl, alkoxy, etc.; R3 and R7 are independently H and alkoxy; R5 is H, alkylamino, alkyl, cycloalkyl, etc.; Cy is (un)substituted Ph] were claimed and prepared The inventive compound has good inhibitory action on tyrosine kinase, and can be applied in treating the proliferative diseases caused by tyrosine kinase. The experimental process involved the reaction of N-(3-Aminophenyl)acrylamide(cas: 16230-24-3).Synthetic Route of 16230-24-3
The Article related to preparation boron tyrosine kinase inhibitor treatment proliferative disease, Organometallic and Organometalloidal Compounds: Boron Compounds and other aspects.Synthetic Route of 16230-24-3
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