Wu, Chenggui; Cheng, Hong-Gang; Chen, Ruiming; Chen, Han; Liu, Ze-Shui; Zhang, Jingyang; Zhang, Yuming; Zhu, Yuxin; Geng, Zhi; Zhou, Qianghui published an article in 2018, the title of the article was Convergent syntheses of 2,3-dihydrobenzofurans via a Catellani strategy.COA of Formula: C11H9NO3 And the article contains the following content:
A cooperative catalytic system comprising a Pd/XPhos complex and a potassium salt of 5-norbornene-2-carboxylic acid to promote the annulation between aryl iodides and epoxides was developed, thereby providing highly convergent access to valuable 2,3-dihydrobenzofuran (DHBF) scaffolds. The unique potassium salt of the inexpensive 5-norbornene-2-carboxylic acid serves as a highly efficient catalytic mediator (10 mol%), which leads to fewer side reactions. The salient features of the reaction include its broad substrate scope (with respect to both aryl iodides and epoxides), its high atom economy and good chemo-selectivity. Furthermore, no extra base is needed for the process. The experimental process involved the reaction of 2-(Oxiran-2-ylmethyl)isoindoline-1,3-dione(cas: 5455-98-1).COA of Formula: C11H9NO3
The Article related to dihydrobenzofuran preparation, aryl iodide epoxide annulation palladium norbornene carboxylic acid catalyst, Heterocyclic Compounds (One Hetero Atom): Areno- and Diarenofurans and other aspects.COA of Formula: C11H9NO3
Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics