Uttam, Surana et al. published their patent in 2012 |CAS: 5455-98-1

On May 29, 2012, Uttam, Surana; Krishnan, Vaidehi; Ting, Anthony; Lim, Hong Hwa published a patent.HPLC of Formula: 5455-98-1 The title of the patent was Naphthalamide derivatives having antiproliferative activity. And the patent contained the following:

The invention relates to compounds for use in medicine. The compounds are of general formula (I) as disclosed herein and the pharmaceutically acceptable salts, individual isomers and mixtures of isomers thereof, wherein X, X’ and X are independently O or S; Z is N or P; R3 is optional and is selected from the group consisting of optionally substituted C1-8 alkyl, optionally substituted C2-6alkenyl, optionally substituted C2-6 alkynyl, optionally substituted C1-6 alkoxy, optionally substituted C1-6 thioalkyl, optionally substituted C5-10 aryl, optionally substituted C6-11 alkylaryl, optionally substituted C1-6 alkylamino, optionally substituted C1-6 alkylcarbonyl, optionally substituted C1-6 alkylsulfonamino, optionally substituted (C1-C6)alkylsulfinyl, optionally substituted C1-6 alkylcarbonylamino, optionally substituted hetero(C4-C10)aryl, hydroxyl, halogen, cyano, nitro, amino, formyl, and thiol; R1, R2, R4, R5, R6, R7, R8, R9, and R10 are independently selected from the group consisting of hydrogen, optionally substituted C1-8 alkyl, optionally substituted C2-6 alkenyl, optionally substituted C2-6 alkynyl, optionally substituted C1-6 alkoxy, optionally substituted C1-6 thioalkyl, optionally substituted C5-10 aryl, optionally substituted C6-11 alkylaryl, optionally substituted C1-6 alkylamino, optionally substituted C1-6 alkylcarbonyl, optionally substituted C1-6 alkylsulfonamino, optionally substituted (C1-C6)alkylsulfinyl, optionally substituted C1-6 alkylcarbonylamino, optionall. The experimental process involved the reaction of 2-(Oxiran-2-ylmethyl)isoindoline-1,3-dione(cas: 5455-98-1).HPLC of Formula: 5455-98-1

The Article related to naphthalamide derivative antiproliferative agent, antitumor agent naphthalamide derivative, antifungal agent naphthalamide derivative, Pharmacology: Effects Of Neoplasm Inhibitors and Cytotoxic Agents and other aspects.HPLC of Formula: 5455-98-1

Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics