Siddique, Nadeem Ahmad; Mujeeb, Mohd.; Najmi, Abul Kalam; Aftab, A.; Aslam, Junaid published an article in 2011, the title of the article was Free radical scavenging and hepatoprotective activity of Aegle marmelos (Linn.) corr leaves against carbon tetrachloride.Related Products of 456-12-2 And the article contains the following content:
Aegle marmelos L. belongs to the family Rutaceae; an important medicinal plant being used in the folk therapy. It is the most useful medicinal plant of India. Its medicinal properties have been described in the ancient medical literature. All parts of the tree (stem, bark, root, leaves and fruit at all stages of maturity) have medicinal virtues and have been used as medicine for a long time. A number of chem. constituents have been isolated from various plant parts including alkaloids, coumarin and steroids. The leaves contain skimianinc, sterol and aegelin. In the present investigation antioxidant and hepatoprotective activity of the methanolic extract of A. marmelos leaves (MEAML) was examined on carbon tetrachloride (CCl4) intoxicated rats. MEAML hold considerable amount of phenolic (9.8367 ± 0.0235 mg/kg) and flavonoid (8.248 ± 0.029 mg/kg) contents, which confirmed the antioxidant property of the leaves. The MEAML with different doses (50, 100, 200 mg/kg body weight) and standard silymarin (40 mg/kg body weight) were orally administered to CCl4 treated rats and the effect was studied on serum enzymes [(aspartate transaminase (AST), alanine transaminase (ALT), alk. phosphatase (ALP), and bilurubin, protein, albumin, thiobarbutiric acid (TBARS), reduced glutathione (GSH)]. In addition, in-vitro antioxidant activity of MEAML was also evaluated using 1,1-diphenyl-2-picryl hydrazyl (DPPH) radical. We noticed a significant hepatoprotective activity of MEAML on CCl4 intoxicated rats which support folkloric utilization of A. marmelos, and it was further confirmed by the histol. investigation. The findings of the present investigation revealed that the MEAML possess significant hepatoprotective activity by suppressing CCl4 induced cellular oxidative stress. The experimental process involved the reaction of N-(2-Hydroxy-2-(4-methoxyphenyl)ethyl)cinnamamide(cas: 456-12-2).Related Products of 456-12-2
The Article related to oxidative stress, hepatoprotectant free radical scavenger aegle leaf carbon tetrachloride antioxidant, Pharmacology: Other (All Agents and Effects Not Otherwise Assignable) and other aspects.Related Products of 456-12-2
Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics