Krais, Annette M.; Essig, Julie Y.; Gren, Louise; Vogs, Carolina; Assarsson, Eva; Dierschke, Katrin; Nielsen, Joern; Strandberg, Bo; Pagels, Joakim; Broberg, Karin; Lindh, Christian H.; Gudmundsson, Anders; Wierzbicka, Aneta published an article in 2021, the title of the article was Biomarkers after controlled inhalation exposure to exhaust from Hydrogenated vegetable oil (HVO).Recommanded Product: 27115-50-0 And the article contains the following content:
Hydrogenated vegetable oil (HVO) is a renewable diesel fuel used to replace petroleum diesel. The organic compounds in HVO are poorly characterized; therefore, toxicol. properties could be different from petroleum diesel exhaust. The aim of this study was to evaluate the exposure and effective biomarkers in 18 individuals after short-term (3 h) exposure to HVO exhaust and petroleum diesel exhaust fumes. Liquid chromatog. tandem mass spectrometry was used to analyze urinary biomarkers. A proximity extension assay was used for the measurement of inflammatory proteins in plasma samples. Short-term (3 h) exposure to HVO exhaust (PM1 ~1μg/m3 and ~90μg/m3 for vehicles with and without exhaust aftertreatment systems, resp.) did not increase any exposure biomarker, whereas petroleum diesel exhaust (PM1 ~300μg/m3) increased urinary 4-MHA, a biomarker for p-xylene. HVO exhaust from the vehicle without exhaust aftertreatment system increased urinary 4-HNE-MA, a biomarker for lipid peroxidation, from 64 ng/mL urine (before exposure) to 141 ng/mL (24 h after exposure, p < 0.001). There was no differential expression of plasma inflammatory proteins between the HVO exhaust and control exposure group. In conclusion, short-term exposure to low concentrations of HVO exhaust did not increase urinary exposure biomarkers, but caused a slight increase in lipid peroxidation associated with the particle fraction. The experimental process involved the reaction of 2-(4-Methylbenzamido)acetic acid(cas: 27115-50-0).Recommanded Product: 27115-50-0
The Article related to hydrogenated vegetable oil inhalation exposure biomarker, hvo, aerosol, biomarkers, exposure studies, lipid peroxidation, renewable diesel, Fossil Fuels, Derivatives, and Related Products: Crude-Oil Refining and other aspects.Recommanded Product: 27115-50-0
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