On March 12, 2022, Dannatt, Jonathan E.; Yadav, Anshu; Smith, Milton R. III; Maleczka, Robert E. Jr. published an article.Application of 685-91-6 The title of the article was Amide directed iridium C(sp3)-H borylation catalysis with high N-methyl selectivity. And the article contained the following:
A bidentate monoanionic ligand system was developed to enable iridium catalyzed C(sp3)-H activation borylation of N-Me amides. Borylated amides were obtained in moderate to good isolated yields, and exclusive mono-borylation allowed the amide to be the limiting reagent. Selectivity for C(sp3)-H activation was demonstrated in the presence of sterically available C(sp3)-H bonds. Competitive kinetic isotope studies revealed a large primary isotope effect, implicating C-H activation as the rate limiting step. The experimental process involved the reaction of N,N-Diethylacetamide(cas: 685-91-6).Application of 685-91-6
The Article related to amide directing group iridium catalyst borylation selective bond activation, boronic ester preparation selective, Organometallic and Organometalloidal Compounds: Boron Compounds and other aspects.Application of 685-91-6
Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics