On July 31, 2020, Haggam, Reda A.; Soylem, Essam. A.; Assy, Mohamed. G.; Arastiedy, Marium. F. published an article.Category: amides-buliding-blocks The title of the article was Synthesis and antimicrobial evaluation of new series of quinazolin-5-one derivatives. And the article contained the following:
A new series of quinazolinone derivatives, e.g., I, were synthesized starting with anthranilic acid and cinnamoylisothiocyanate in high yields 55-99%. The study of the biol. activity of all the novel compounds is reported. The minimal inhibitory concentration of some quinazolin-5-one derivatives, e.g., I, showed potential activity against both Gram (+ve) and Gram (-ve) microorganisms more than the reference cefotaxime. In addition, some derivatives of quinazolin-5-one, e.g., I, can be considered as antifungal agents comparing with the standard drug nystatin. The experimental process involved the reaction of 2-Chloroacetamide(cas: 79-07-2).Category: amides-buliding-blocks
The Article related to quinazolinone preparation antibacterial antifungal activity, Heterocyclic Compounds (More Than One Hetero Atom): Pyrimidines and Quinazolines and other aspects.Category: amides-buliding-blocks
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Amide – Wikipedia,
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