On May 1, 2012, Takahashi, Daisuke; Honda, Yutaka; Izawa, Kunisuke published an article.Product Details of 27115-50-0 The title of the article was Syntheses of 5-amino-2-phenyl-4(3H)-pyrimidinone derivatives starting with glycine. And the article contained the following:
N-Cbz-5-amino-2-phenyl-4(3H)-pyrimidinone was prepared from the Na salt of Me (hydroxymethylene)glycinate and benzamidine.HCl in good yield. However, the reaction with N-substituted benzamidine did not proceed to give the desired pyrimidinone. In contrast, the reaction of 4-ethoxymethylene-2-phenyl-5(4H)-oxazolone, readily prepared from hippuric acid and N-substituted benzamidine, proceeded nicely to give 5-(benzoylamino)-6-oxo-2-phenyl-1(6H)-pyrimidineacetate in high yield. The experimental process involved the reaction of 2-(4-Methylbenzamido)acetic acid(cas: 27115-50-0).Product Details of 27115-50-0
The Article related to glycine benzamidine cyclocondensation, hippuric acid benzamidine cyclocondensation, aminopyrimidinone preparation, pyrimidinone amino preparation, Heterocyclic Compounds (More Than One Hetero Atom): Pyrimidines and Quinazolines and other aspects.Product Details of 27115-50-0
Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics