Chandraprakash, B.; Sarangapani, M. published an article in 2021, the title of the article was Synthesis, characterization, anticancer and antibacterial activity of 4-(benzylidene)-1-(pyrimidin-2-amino)-2-(p-tolyl)-1, 4-dihydro-4H-imidazol-5-one.Name: 2-(4-Methylbenzamido)acetic acid And the article contains the following content:
In present study, conventional synthesis of 4-(benzylidene)-1-(pyrimidin-2-amino)-2-(p-tolyl)-1, 4-dihydro-4H-imidazol-5-ones I [R = H, Me, Cl, etc.; R1 = H, MeO, NO2] was performed. All the synthesized products I were purified through column chromatog. and structures of these compounds were characterized by IR, 1H NMR and mass spectral data. All the final compounds I were screened for their anticancer and antibacterial activity and their efficacy were matched with standard drugs. The synthesized compounds I [R = Me, NO2, MeO, Br; R1 = H, MeO] showed good anticancer activities whereas others exhibited significant activities. The compounds I [R = Cl, MeO, NO2; R1 = H, MeO] has showed maximum antibacterial activity compare with streptomycin as a standard drug. The experimental process involved the reaction of 2-(4-Methylbenzamido)acetic acid(cas: 27115-50-0).Name: 2-(4-Methylbenzamido)acetic acid
The Article related to benzylidene pyrimidinyl amino tolyl dihydroimidazolone preparation antibacterial antitumor, Heterocyclic Compounds (More Than One Hetero Atom): Pyrimidines and Quinazolines and other aspects.Name: 2-(4-Methylbenzamido)acetic acid
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