On November 30, 2011, Suzdalev, K. F.; Den’kina, S. V. published an article.Recommanded Product: 2-(4-Methylbenzamido)acetic acid The title of the article was Synthesis of 1-(oxiran-2-ylmethyl)-1H-indole-3-carbaldehyde and its reaction with active methylene compounds. And the article contained the following:
Treatment of indole-3-carbaldehyde with epichlorohydrin gave 1-(oxiran-2-ylmethyl)-1H-indole-3-carbaldehyde, reaction of which with 1,3-dimethylbarbituric acid or malononitrile gave crotonic condensation products with retention of the oxirane ring. The structure of the reaction products with aroylglycines depends on the conditions. In acetic anhydride a simultaneous formation of an oxazolone ring and bisacylation of the oxirane fragment occurs; the use of Et chloroformate in the presence of triethylamine resulted in only the heterocyclization process. When treated with the cyclic amines (N-methylpiperazine or morpholine), opening of the oxazolone ring in the products occurs with formation of the corresponding amides. The experimental process involved the reaction of 2-(4-Methylbenzamido)acetic acid(cas: 27115-50-0).Recommanded Product: 2-(4-Methylbenzamido)acetic acid
The Article related to oxiranylmethylindolecarbaldehyde preparation reaction active methylene compound, indolecarbaldehyde oxiranylmethyl preparation reaction active methylene compound, Heterocyclic Compounds (One Hetero Atom): Indoles, Indolizines, Carbazoles, and Other Arenopyrroles and other aspects.Recommanded Product: 2-(4-Methylbenzamido)acetic acid
Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics