On May 5, 2006, Marko, Istvan; De Paolis, Michael; Mignani, Gerard published a patent.Computed Properties of 167316-28-1 The title of the patent was Use of an aromatic carboxylic acid in an asymmetric catalysis reaction, particularly Aldol condensation, in combination with pyrrolidine-containing chiral derivatives of diamines, amino alcohols, carbonyls, and monosulfonyl compounds. And the patent contained the following:
The invention is related to the use of strong aromatic carboxylic acids of formula I [B = aromatic carbocycle; L = alkyl(en)yl; n = number of R substituents, especially 1-2; each R = independently various substituents on ring B, with at least 1 substituent representing an electron attracting group] in combination with pyrrolidine-containing chiral catalysts such as derivatives of diamines, amino alcs., carbonyls, monosulfonyl compounds, in asym. catalysis, particularly asym. aldolization or ketolization. Thus, 2-nitrobenzoic acid in combination with 2-pyrrolidinamide derivative II was used in an aldolization reaction of 4-nitrobenzaldehyde in CH3CN-H2O-acetone. The experimental process involved the reaction of N-[(1S,2S)-2-Amino-1,2-diphenylethyl]-1,1,1-trifluoromethanesulfonamide(cas: 167316-28-1).Computed Properties of 167316-28-1
The Article related to asym aldolization aryl carboxylic acid, aldol preparation asym catalysis, chiral catalyst asym aldol condensation, Benzene, Its Derivatives, and Condensed Benzenoid Compounds: Ketones and Derivatives, Including Quinones and Sulfur Analogs and other aspects.Computed Properties of 167316-28-1
Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics