On November 24, 2017, Chen, Wenteng; Liu, Xingyu; Shao, Jiaan; Chen, En; Yu, Yongping published a patent.Application of 16230-24-3 The title of the patent was Preparation of 2-aminooimidazole pyridine derivatives as antitumor agents. And the patent contained the following:
The invention provides 2-aminooimidazole pyridine derivatives and method for preparing them, therfore. Experiments prove that the derivative has obvious proliferation inhibition effect on tumor cells (human epidermal carcinoma cell strain A431 overexpressing wild type EGFR, and Gefitinib-resistant human lung adenocarcinoma cell strain H1975) related with activity of EGFR tyrosine kinase activity at mol. level, particularly has preferable inhibition on drug-resistant cell strain H1975, has weak inhibitory activity on human colon cancer cell strain SW620 low expressing EGFR, and can be applied to prepare corresponding tumor cell-resistant drugs. The experimental process involved the reaction of N-(3-Aminophenyl)acrylamide(cas: 16230-24-3).Application of 16230-24-3
The Article related to aminooimidazole pyridine preparation antitumor, Heterocyclic Compounds (More Than One Hetero Atom): Pyrazines and Quinoxalines (Including Piperazines) and other aspects.Application of 16230-24-3
Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics