Barham, Joshua P.; Tamaoki, Souma; Egami, Hiromichi; Ohneda, Noriyuki; Okamoto, Tadashi; Odajima, Hiromichi; Hamashima, Yoshitaka published an article in 2018, the title of the article was C-Alkylation of N-alkylamides with styrenes in air and scale-up using a microwave flow reactor.Product Details of 685-91-6 And the article contains the following content:
C-Alkylation of N-alkylamides with styrenes is reported, proceeding in ambient air/moisture to give arylbutanamides and pharmaceutically-relevant scaffolds in excellent mass balance. Various amide and styrene derivatives were tolerated, rapidly affording mol. complexity in a single step; thus highlighting the future utility of this transformation in the synthetic chem. toolbox. Reaction scalability (up to 65 g h-1 product) was demonstrated using a microwave flow reactor, as the first example of a C-alkylation reaction using styrenes in continuous flow. The experimental process involved the reaction of N,N-Diethylacetamide(cas: 685-91-6).Product Details of 685-91-6
The Article related to arylbutanamide preparation microwave flow reactor, alkylamide styrene alkylation, Benzene, Its Derivatives, and Condensed Benzenoid Compounds: Amides, Amidines, Imidic Esters, Hydrazides, and Hydrazonic Esters and other aspects.Product Details of 685-91-6
Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics