Mohammed, Magdy M. D.; Ibrahim, Nabaweya A.; El-Sakhawy, Fatma S.; Mohamed, Khaled M.; Deabes, Doaa A.-H. published an article in 2016, the title of the article was Two new cytotoxic furoquinoline alkaloids isolated from Aegle marmelos (Linn.) Correa.Application In Synthesis of N-(2-Hydroxy-2-(4-methoxyphenyl)ethyl)cinnamamide And the article contains the following content:
Two new cytotoxic furoquinoline alkaloids were isolated from the leaves of Aegle marmelos (Linn.) Correa; one from the total alkaloidal fraction (acid/base shake-out method) of the CHCl3 extract and identified as 7,8-dihydroxy-4-hydrofuroquinoline and named trivially as Aegelbine-A. The other new alkaloid isolated from the pet. ether extract and identified as 4-hydro-7-hydroxy-8-prenyloxyfuroquinoline and named trivially as Aegelbine-B, together with a known alkaloid; aegeline and a known phenolic acid; ρ-hydroxybenzoic acid. The structures of all the isolated compounds were established based on 1D and 2D NMR spectroscopy and HR-ESI/MS. The cytotoxic activity of the isolated compounds was evaluated in vitro against HepG-2, PC3, A549 and MCF-7 cell lines. The obtained results revealed promising activity with structure-based relationship which is discussed briefly. The experimental process involved the reaction of N-(2-Hydroxy-2-(4-methoxyphenyl)ethyl)cinnamamide(cas: 456-12-2).Application In Synthesis of N-(2-Hydroxy-2-(4-methoxyphenyl)ethyl)cinnamamide
The Article related to mol structure cytotoxic furoquinoline alkaloid aegle aegelbine human antitumor, aegle marmelos (linn.) correa, cytotoxicity, furoquinoline alkaloids, rutaceae, structure–activity relationship studies and other aspects.Application In Synthesis of N-(2-Hydroxy-2-(4-methoxyphenyl)ethyl)cinnamamide
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