On August 4, 2017, Matsuzawa, Akinobu; Noda, Hidetoshi; Kumagai, Naoya; Shibasaki, Masakatsu published an article.Reference of N,N-Diethylacetamide The title of the article was Direct Catalytic Asymmetric Aldol Addition of an α-CF3 Amide to Arylglyoxal Hydrates. And the article contained the following:
Direct asym. aldol addition of an α-CF3 amide to arylglyoxal hydrates was promoted by a chiral catalyst comprising a soft Lewis acidic Cu(I), a chiral bisphosphine ligand, and DBU. The 7-azaindoline moiety of the amide facilitates its enolization and stabilizes the thus-generated Cu enolate, furnishing enantioenriched aldol adducts. The experimental process involved the reaction of N,N-Diethylacetamide(cas: 685-91-6).Reference of N,N-Diethylacetamide
The Article related to asym aldol addition alpha trifluoromethyl amide arylglyoxal hydrate, copper catalyzed addition azaindoline moiety enantioenriched aldol adduct preparation, Heterocyclic Compounds (More Than One Hetero Atom): Fused-Ring Systems With Two Or More Hetero Atoms, No More Than One Hetero Atom Per Ring and other aspects.Reference of N,N-Diethylacetamide
Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics