On October 25, 2007, Kansal, Kinod Kumar; Ahmad, Suhail; Mariappan, Shanmugavel; Tyagi, Bhupendra; Perlman, Nurit; Le Paih, Jacques; Zanotti-Gerosa, Antonio published a patent.Recommanded Product: N-[(1S,2S)-2-Amino-1,2-diphenylethyl]-1,1,1-trifluoromethanesulfonamide The title of the patent was Processes for the synthesis of azetidinone. And the patent contained the following:
Provided were intermediates useful for the synthesis of hydroxyl-alkyl substituted azetidinones, processes of their preparation and processes for the synthesis of certain hydroxyl-alkyl substituted azetidinones. Also provided were processes for the synthesis of 1-(4-fluorophenyl)-3(R)-[3-(4-fluorophenyl)-3(S)-hydroxypropyl]-4(S)-(4-hydroxyphenyl)-2-azetidinone, or ezetimibe (I). The experimental process involved the reaction of N-[(1S,2S)-2-Amino-1,2-diphenylethyl]-1,1,1-trifluoromethanesulfonamide(cas: 167316-28-1).Recommanded Product: N-[(1S,2S)-2-Amino-1,2-diphenylethyl]-1,1,1-trifluoromethanesulfonamide
The Article related to azetidinone ezetimibe analog preparation drug delivery system, cholesterol absorption inhibitor azetidinone ezetimibe analog preparation, stereoselective reduction ruthenium catalyst ezetimibe preparation and other aspects.Recommanded Product: N-[(1S,2S)-2-Amino-1,2-diphenylethyl]-1,1,1-trifluoromethanesulfonamide
Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics