Zhang, Haolin’s team published research in Chem in 2022 | CAS: 71432-55-8

tert-Butyl N,N’-diisopropylcarbamimidate(cas: 71432-55-8) belongs to anime. Amines have a free lone pair with which they can coordinate to metal centers. Amine–metal bonds are weaker because amines are incapable of backbonding, but they are still important for sensing applications.While stronger than hydrogen bonds, amine–metal bonds are still weaker than both covalent and ionic bonds.Reference of tert-Butyl N,N’-diisopropylcarbamimidate

Reference of tert-Butyl N,N’-diisopropylcarbamimidateIn 2022 ,《New rhodamines with changeable Π-conjugation for lengthening fluorescence wavelengths and imaging peroxynitrite》 appeared in Chem. The author of the article were Zhang, Haolin; Xu, Yanhui; Li, Hongyu; Shi, Wen; Li, Xiaohua; Ma, Huimin. The article conveys some information:

Rhodamines, a group of excellent fluorophores, have been widely used to design various fluorescent probes; however, their maximum emission wavelengths are relatively short for bioimaging. Herein, we report a new kind of rhodamine derivatives characterized by the dibenzo[1,4]oxazepine core, which can selectively react with peroxynitrite (ONOO-), generating oxazines with much longer anal. wavelengths. These derivatives are readily synthesized in one step via a similar Stieglitz rearrangement; the presence of the 1,4-oxazepine ring is confirmed by single-crystal X-ray. Most importantly, the derivative (ON-RB) from rhodamine B, upon reaction with ONOO-, releases the oxazine moiety that emits in the near-IR wavelength region. Using ON-RB, we have monitored the generation of ONOO- in macrophage-derived foam cells, revealing that ONOO- might be formed mainly in lipid droplets. The new chem. of the dibenzo[1,4]oxazepine ring formation, together with its specific reaction with ONOO-, may provide a convenient strategy to develop rhodamine-based probes with longer wavelengths. The experimental process involved the reaction of tert-Butyl N,N’-diisopropylcarbamimidate(cas: 71432-55-8Reference of tert-Butyl N,N’-diisopropylcarbamimidate)

tert-Butyl N,N’-diisopropylcarbamimidate(cas: 71432-55-8) belongs to anime. Amines have a free lone pair with which they can coordinate to metal centers. Amine–metal bonds are weaker because amines are incapable of backbonding, but they are still important for sensing applications.While stronger than hydrogen bonds, amine–metal bonds are still weaker than both covalent and ionic bonds.Reference of tert-Butyl N,N’-diisopropylcarbamimidate

Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics