In 2010,Vanek, V.; Picha, J.; Budesinsky, M.; Sanda, M.; Jiracek, J.; Holz, R. C.; Hlavacek, J. published 《Synthesis of N-succinyl-L,L-diaminopimelic acid mimetics via selective protection》.Protein & Peptide Letters published the findings.Computed Properties of C11H24N2O The information in the text is summarized as follows:
The search for potential inhibitors that target so far unexplored bacterial enzyme mono-N-succinyl-L,L-diaminopimelic acid desuccinylase (DapE) has stimulated a development of methodol. for quick and efficient preparation of mono-N-acylated 2,6-diaminopimelic acid (DAP) derivatives bearing different carboxyl groups or lipophilic moieties on their amino group. In addition to this study using tert-Butyl N,N’-diisopropylcarbamimidate, there are many other studies that have used tert-Butyl N,N’-diisopropylcarbamimidate(cas: 71432-55-8Computed Properties of C11H24N2O) was used in this study.
tert-Butyl N,N’-diisopropylcarbamimidate(cas: 71432-55-8) belongs to anime. The reaction of alkyl halides, R―X, where X is a halogen, or analogous reagents with ammonia (or amines) is useful with certain compounds. Not all alkyl halides are effective reagents; the reaction is sluggish with secondary alkyl groups and fails with tertiary ones. Its usefulness is largely confined to primary alkyl halides (those having two hydrogen atoms on the reacting site).Computed Properties of C11H24N2O
Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics