In 2019,Chemical Science included an article by Tang, Nana; Wu, Xinxin; Zhu, Chen. Computed Properties of C7H9NO2S. The article was titled 《Practical, metal-free remote heteroarylation of amides via unactivated C(sp3)-H bond functionalization》. The information in the text is summarized as follows:
A new, efficient, site-selective heteroarylation of amides via C(sp3)-H bond functionalization. Amidyl radicals were directly generated from the amide N-H bonds under mild conditions, which triggered the subsequent 1,5-HAT process. A wide scope of aliphatic amides including carboxamides, sulfonamides and phosphoramides were readily modified at remote C(sp3)-H bonds by installing diverse heteroaryl groups. Borne out of pragmatic consideration, this protocol was used for the late-stage functionalization of amides. In the experiment, the researchers used 4-Methylbenzenesulfonamide(cas: 70-55-3Computed Properties of C7H9NO2S)
4-Methylbenzenesulfonamide(cas: 70-55-3) belongs to anime. Many important products require amines as part of their syntheses. Methylamine is utilized in the production of the analgesic meperidine (trade name Demerol) and the photographic developer Metol (trademark), and dimethylamine is used in the synthesis of the antihistamine diphenhydramine (trade name Benadryl), the solvent dimethylformamide (DMF), and the rocket propellant 1,1-dimethylhydrazine. The synthesis of the insect repellent N,N-diethyl-m-toluamide (DEET) incorporates diethylamine while that of the synthetic fibre Kevlar requires aromatic amines.Computed Properties of C7H9NO2S
Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics