In 1986,Tetrahedron Letters included an article by Shin, Jai Moo; Kim, Yong Hae. Computed Properties of C8H9NO2. The article was titled 《New facile synthesis of α-hydroxy amides: intermolecular and intramolecular catalysis in the reaction of α-hydroxy carboxylic acids with N-sulfinylamines》. The information in the text is summarized as follows:
α-Hydroxy carboxylic acids reacted with N-sulfinylanilines to give the corresponding α-hydroxy anilides in quant. yields under mild condition. The reaction appeared to involve intermol. catalysts by the carboxylic acid moiety and intramol. catalysis by the HO group. Thus, DL-mandelic acid in MeCN treated with PhN:S:O gave 100% DL-mandelanilide.2-Hydroxy-N-phenylacetamide(cas: 4746-61-6Computed Properties of C8H9NO2) was used in this study.
2-Hydroxy-N-phenylacetamide(cas: 4746-61-6) belongs to amides.Computed Properties of C8H9NO2 The solubilities of amides and esters are roughly comparable. Typically amides are less soluble than comparable amines and carboxylic acids since these compounds can both donate and accept hydrogen bonds.
Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics