Schaefer, Olga; Schollmeyer, Dieter; Birke, Alexander; Holm, Regina; Johann, Kerstin; Muhl, Christian; Seidl, Christine; Weber, Benjamin; Barz, Matthias published an article on January 17 ,2019. The article was titled 《Investigation of α-amino acid N-carboxyanhydrides by X-ray diffraction for controlled ring-opening polymerization》, and you may find the article in Tetrahedron Letters.Reference of H-Lys(Boc)-OH The information in the text is summarized as follows:
The need for a scalable synthesis of not sequence defined polypeptides as biomaterials is met by the ring-opening polymerization of α-amino acid N-carboxyanhydrides (NCAs). Even though this polymerization technique appears straight forward, it holds pitfalls in terms of reproducibility and overall control over the polymerization conditions, which depends, beside choice of solvent or initiator, significantly on reagent purity. In addition, the synthesis of monomers can lead to the formation of racemic amino acids. Thus, in this work, we describe the benefits of highly pure monomers in order to control nucleophilic ring-opening polymerization NCAs. Hereby, monomer purity is investigated by relating m.ps. of NCAs with single-crystal and powder X-ray diffraction crystallog. data, which further proves retained stereo-information of NCAs. In the experimental materials used by the author, we found H-Lys(Boc)-OH(cas: 2418-95-3Reference of H-Lys(Boc)-OH)
H-Lys(Boc)-OH(cas: 2418-95-3) belongs to amino acids. In addition to subunits of proteins, amino acids have many other functions as well, including osmoregulation (proline), neurotransmitters (gamma-aminobutyric acid), metabolic intermediates (ornithine and citrulline), and inhibitors (dehydroproline).Reference of H-Lys(Boc)-OH
Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics