Synthetic Route of C10H14N2OOn March 15, 2011, Metro, Thomas-Xavier; Fayet, Christine; Arnaud, Florian; Rameix, Nathalie; Fraisse, Pierre; Janody, Simon; Sevrin, Mireille; George, Pascal; Vogel, Rachel published an article in Synlett. The article was 《Synthesis of 2,2-disubstituted azaindolines by intramolecular cyclization in acidic media》. The article mentions the following:
The synthesis of a diverse array of 2,2-disubstituted azaindolines, e.g. I, is reported. The bicyclic core is built by a simple acidic treatment of conveniently substituted aminopyridines. The results came from multiple reactions, including the reaction of 2,2-Dimehtyl-N-pyridin-3-yl-propionamide(cas: 70298-88-3Synthetic Route of C10H14N2O)
2,2-Dimehtyl-N-pyridin-3-yl-propionamide(cas: 70298-88-3) belongs to anime. Large quantities of aliphatic amines are made synthetically. The most widely used industrial method is the reaction of alcohols with ammonia at a high temperature, catalyzed by metals or metal oxide catalysts (e.g., nickel or copper). Mixtures of primary, secondary, and tertiary amines are thereby produced.Synthetic Route of C10H14N2O
Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics