《Synthesis of 3-hydroxy-1,3-dihydro-2H-pyrrolo[2,3-b]-, -[2,3-c]-, or -[3,2-c]pyridin-2-ones from the respective N-pyridinylpivalamides and α-keto esters》 was published in Heterocycles in 2016. These research results belong to Kobayashi, Kazuhiro; Kosuna, Risa; Chikazawa, Yuuki. HPLC of Formula: 70298-88-3 The article mentions the following:
A convenient synthesis of the dihydro pyrrolopyridinones, e.g., I by reaction of N-(pyridinyl)pivalamides with α-keto esters via in situ generated dilithium compounds is described. Thus, N-(3-lithiopyridin-2-yl)pivalamide reacts smoothly leading to the formation of the corresponding α-hydroxy esters. These α-hydroxy esters underwent deprotective cyclization in refluxing hydrochloric acid to afford 3-substituted 3-hydroxy-1,3-dihydro-2H-pyrrolo[2,3-b]pyridin-2-ones. Similarly, starting from N-(pyridin-3- or -4-yl)pivalamides, the corresponding 3-dihydro-2H-pyrrolo[2,3- c]- or -[3,2-c]pyridin-2-one derivatives can be prepd resp. After reading the article, we found that the author used 2,2-Dimehtyl-N-pyridin-3-yl-propionamide(cas: 70298-88-3HPLC of Formula: 70298-88-3)
2,2-Dimehtyl-N-pyridin-3-yl-propionamide(cas: 70298-88-3) belongs to anime. Amines can be classified according to the nature and number of substituents on nitrogen. Aliphatic amines contain only H and alkyl substituents. Aromatic amines have the nitrogen atom connected to an aromatic ring.Important amines include amino acids, biogenic amines, trimethylamine, and aniline. Inorganic derivatives of ammonia are also called amines, such as monochloramine (NClH2).HPLC of Formula: 70298-88-3
Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics