Han, Lu; Zhang, Xue-Ting; Xie, Dong; Tian, Shi-Kai published an article in 2021. The article was titled 《Aryne-mediated [2,3]-sigmatropic rearrangement of tertiary 2,3-allenylamines bearing an electron-withdrawing group at the α-position》, and you may find the article in Organic & Biomolecular Chemistry.Product Details of 683-57-8 The information in the text is summarized as follows:
An unprecedented [2,3]-sigmatropic rearrangement reaction of quaternary 2,3-allenylammonium ylides, generated in-situ from tertiary 2,3-allenylamines and arynes, was established. With 2-(trimethylsilyl)aryl triflates as aryne precursors, a range of tertiary 2,3-allenylamines bearing an electron-withdrawing group at the α-position smoothly participated in the aryne-mediated [2,3]-sigmatropic rearrangement at room temperature, delivering structurally diverse 2-vinylallyamines or 1-amino-1,3-dienes in moderate to excellent yields. The reaction proceeded in the absence of strong bases and transition metals, was compatible with moisture and air and tolerated a wide variety of functional groups. In the part of experimental materials, we found many familiar compounds, such as 2-Bromoacetamide(cas: 683-57-8Product Details of 683-57-8)
2-Bromoacetamide(cas: 683-57-8) can be used in preparation of (2-carbamoylmethoxy-5-chloro-benzyl)-carbamic acid tert-butyl ester. It was aslo used as precursor to dehydropeptidase I inactivator.Product Details of 683-57-8
Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics