Recommanded Product: 4-MethylbenzenesulfonamideIn 2019 ,《The N-alkylation of sulfonamides with alcohols in water catalyzed by a water-soluble metal-ligand bifunctional iridium complex [Cp*Ir(biimH2)(H2O)][OTf]2》 was published in New Journal of Chemistry. The article was written by Ai, Yao; Liu, Pengcheng; Liang, Ran; Liu, Yan; Li, Feng. The article contains the following contents:
The iridium complex [Cp*Ir(biimH2)(H2O)][OTf]2 (Cp* = η5-pentamethylcyclopentadienyl, biimH2 = 2,2′-biimidazole) was synthesized and developed as a new-type of water-soluble metal-ligand bifunctional catalyst for the N-alkylation of poorly nucleophilic sulfonamides with alcs. in water. In the presence of catalyst (1 mol%) and Cs2CO3 (0.1 equivalent), a series of desirable products was obtained in 74-91% yields under microwave irradiation Mechanistic experiments revealed that the presence of NH units in the imidazole ligand was crucially important for the catalytic activity of the iridium complex. Notably, this research would facilitate the process of water-soluble metal-ligand bifunctional catalysis for the hydrogen autotransfer process. In the part of experimental materials, we found many familiar compounds, such as 4-Methylbenzenesulfonamide(cas: 70-55-3Recommanded Product: 4-Methylbenzenesulfonamide)
4-Methylbenzenesulfonamide(cas: 70-55-3) belongs to anime. Reduction of nitro compounds, RNO2, by hydrogen or other reducing agents produces primary amines cleanly (i.e., without a mixture of products), but the method is mostly used for aromatic amines because of the limited availability of aliphatic nitro compounds. Reduction of nitriles and oximes (R2C=NOH) also yields primary amines.Recommanded Product: 4-Methylbenzenesulfonamide
Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics