Wang, Gao-Lei’s team published research in Chinese Chemical Letters in 2015-12-31 | 112253-70-0

Chinese Chemical Letters published new progress about Nematocides. 112253-70-0 belongs to class amides-buliding-blocks, and the molecular formula is C7H7BrN2O, Safety of 2-Amino-4-bromobenzamide.

Wang, Gao-Lei; Chen, Xi; Chang, Ya-Ning; Du, Dan; Li, Zhong; Xu, Xiao-Yong published the artcile< Synthesis of 1,2,3-benzotriazin-4-one derivatives containing spirocyclic indoline-2-one moieties and their nematicidal evaluation>, Safety of 2-Amino-4-bromobenzamide, the main research area is spirocycle indolinone benzotriazinone derivative preparation nematicidal.

To discover new chemotypes of nematicides with proper toxicol. profiles, a series of novel 1,2,3-benzotriazin-4-one derivatives were synthesized and further bioevaluated. The bioassay results showed that most of the synthesized compounds were endowed with moderate to good control efficacy against Meloidogyne incognita at 10.0 mg/L in vivo. Among them, compounds 1-(4-(4-oxo-7-methoxylbenzo[d][1,2,3]triazin-3(4H)-yl)butyl)spiro[indoline-3,2′-[1,3]dioxolan]-2-one and 1-(4-(4-oxo-7-nitrobenzo[d][1,2,3]triazin-3(4H)-yl)butyl)spiro[indoline-3,2′-[1,3]dioxolan]-2-one displayed 100% inhibitory activities at this concentration, which implied that they could be used as lead compounds for promising nematicides.

Chinese Chemical Letters published new progress about Nematocides. 112253-70-0 belongs to class amides-buliding-blocks, and the molecular formula is C7H7BrN2O, Safety of 2-Amino-4-bromobenzamide.

Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics