Application of 4746-61-6On October 31, 1982 ,《Regioselectivity of enzymic O-dealkylation of simple analogs of cholecystographic constrast media》 was published in Drug Metabolism and Disposition. The article was written by Shono, Tatsuya; Ohmizu, Yohko; Toda, Toshiki; Oshino, Nozomu. The article contains the following contents:
The metabolites of N,N’-diphenyl-α,ω-polyoxyethylenedicarboxamides following O-dealkylation by rat liver microsomes were identified by high-performance liquid chromatog. The pattern of metabolism of the dicarboxamides followed the same O-dealkylation pattern as that of iotroxic acid. In the part of experimental materials, we found many familiar compounds, such as 2-Hydroxy-N-phenylacetamide(cas: 4746-61-6Application of 4746-61-6)
2-Hydroxy-N-phenylacetamide(cas: 4746-61-6) belongs to amides. The solubilities of amides and esters are roughly comparable. Typically amides are less soluble than comparable amines and carboxylic acids since these compounds can both donate and accept hydrogen bonds.Application of 4746-61-6
Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics